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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396228Generated: November 2, 2026

HCID 12328278, compound → HCID 54011443, compound

https://huagongshe.com/reaction/2396228

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 12328278HCID 12328278—
ReactantPravastatin Diol Lactone Di-(tert-butyldimethylsilyl) EtherHCID 14600906—
ProductHCID 54011443HCID 5401144348.9%

Reaction Steps

A procedure similar to that described in Example 10, above, was followed, but using 0.32 g of (2RS)-2-(4-methylphenoxy)-2-phenylacetic acid and 0.61g of (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above], to give 0.42 g of the title compound as a colorless foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05491167
Source datasetuspto-grants-1996_02
ORD IDord-d97a036010c341eb8fe67a27319ec954
Source noteuspto-grants-1996_02