Tetrabutylammonium Fluoride → HCID 54467089, compound

Participants

Reaction Steps

A procedure similar to that described in Example 2, above, was followed, but using the whole of the fraction (414 mg) containing (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-(2-ethoxy-2-methylpropionyloxy)-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example 151, above] and 6.2 ml of a 1.0 molar solution of tetrabutylammonium fluoride in tetrahydrofuran, to give 25 mg of the titlecompound as colorless needle-like crystals, melting at 132° C.

Provenance & Evidence