Tetrabutylammonium Fluoride → HCID 57046132, compound

Participants

Reaction Steps

A procedure similar to that described in Example 2, above, was followed, but using 200 mg of (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-(2,2-bis[methoxymethyl]propionyloxy)-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example 160, above] and 4.0 ml of a 1.0 molar solution of tetrabutylammonium fluoride in tetrahydrofuran, to give 105 mg of the title compound as colorless needle-like crystals, melting at between 122° and 123° C.

Provenance & Evidence