Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396241Generated: November 2, 2026

3-Methoxy-2,2-dimethylpropanoic acid → HCID 67730956, compound

https://huagongshe.com/reaction/2396241

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methoxy-2,2-dimethylpropanoic acidHCID 3017506—
ReactantPravastatin Diol Lactone Di-(tert-butyldimethylsilyl) EtherHCID 14600906—
ProductHCID 67730956HCID 6773095635%

Reaction Steps

A procedure similar to that described in Example 10, above, was followed, but using 960 mg of 2-methoxymethyl-2-methylpropionic acid and 1.0 g of (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above], to give 423 mg of the title compound as a colorless foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05491167
Source datasetuspto-grants-1996_02
ORD IDord-58833fce8552434eb4bb3f56b47a192d
Source noteuspto-grants-1996_02