Tetrabutylammonium Fluoride → HCID 54029846, compound

Participants

Reaction Steps

A procedure similar to that described in Example 2, above, was followed, but using 1.0 g of (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-(2-methyl-2-phenoxypropionyloxy)-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example 172, above] and 19.6 ml of a 1.0 molar solution of tetrabutylammonium fluoride in tetrahydrofuran, to give 520 mg of the title compound as colorless crystals, melting at between 155° and 158° C.

Provenance & Evidence