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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396253Generated: November 1, 2026

2-Methyl-2-(4-nitrophenoxy)propanoic acid → HCID 54477024, compound

https://huagongshe.com/reaction/2396253

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-2-(4-nitrophenoxy)propanoic acidHCID 176930—
ReactantPravastatin Diol Lactone Di-(tert-butyldimethylsilyl) EtherHCID 14600906—
ProductHCID 54477024HCID 54477024—

Reaction Steps

A procedure similar to that described in Example 1, above, was followed, but using 597 mg of 2-(4-nitrophenoxy)-2-methylpropionic acid and 731 mg of (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above], to give880 mg of the title compound as a colorless foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05491167
Source datasetuspto-grants-1996_02
ORD IDord-6ccbc4772e024a8e94354f5750be9a20
Source noteuspto-grants-1996_02