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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396336Generated: November 3, 2026

Trifluoroacetic acid → HCID 57165336, compound

https://huagongshe.com/reaction/2396336

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 21460793HCID 21460793—
SolventDichloromethaneHCID 6344—
SolventEthyl AcetateHCID 8857—
ProductHCID 57165336HCID 57165336—

Reaction Steps

Dissolve 3-[(phenacyl)methylamino]-2-carbethoxy-6-fluoro-1-(tert-butyloxycarbonyl)-indole from above in methylene chloride (10 mL). Add trifluoracetic acid (3mL) and stir for 4 hours at room temperature. Dilute with ethyl acetate (50mL) and rinse with 1N sodium hydroxide, saturated sodium chloride, dry overmagnesium sulfate, filter and concentrate in vacuo to yield 3-[(phenacyl)methylamino]-2-carbethoxy-6-fluoroindole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05491153
Source datasetuspto-grants-1996_02
ORD IDord-724b325235374212af2be53fc1218187
Source noteuspto-grants-1996_02