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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396342Generated: October 30, 2026

Trifluoroacetic acid → HCID 57279336, compound

https://huagongshe.com/reaction/2396342

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 21460758HCID 21460758—
SolventDichloromethaneHCID 6344—
SolventEthyl AcetateHCID 8857—
ProductHCID 57279336HCID 57279336—

Reaction Steps

Dissolve 3-[(phenacyl)methylamino]-2-carbethoxy-6-nitro-1-(tert-butyloxycarbonyl)-indole from above in methylene chloride. Add excess trifluoracetic acid and stir overnight at room temperature. Concentrate the reaction in vacuo, dilute with ethyl acetate and rinse with saturated sodium bicarbonate, dryover magnesium sulfate, filter and concentrate in vacuo to yield 3-[(phenacyl)methylamino]-2-carbethoxy-6-nitroindole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05491153
Source datasetuspto-grants-1996_02
ORD IDord-a4f8202e925c446499029a08a25ae760
Source noteuspto-grants-1996_02