HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 57224895, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 57205555 | HCID 57205555 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 57224895 | HCID 57224895 | — |
Reaction Steps
Mix 3-[(p-chlorophenacyl)methylamino]-2-carbethoxy-4,6-dichloroindole (1.3 g, 3.1 mmol), excess lithium hydroxide, tetrahydrofuran and water and stirovernight. Dilute with ethyl acetate and separate the layers. Dry the organic phase over magnesium sulfate, filter and concentrate in vacuo to yield the title compound; mp 279°-283° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05491153 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-f219c453db644d5c859f46d60611a463 |
| Source note | uspto-grants-1996_02 |