Hydrochloric Acid → HCID 60209019, compound

Participants

Reaction Steps

To a solution of Example 2 (0.10 g, 0.249 mmoles) in THF (2 ml), was added hydrochloric acid in diethyl ether (2 ml) at 0° C. and stirred for 30 min. The precipitate formed was filtered, washed with pentane and dried to afford the title compound as pale yellow solid(0.110 g, 99% yield. MP: 229-230° C. 1H-NMR (δ ppm, DMSO-D6, 400 MHz): δ 8.13(s, 1H), 8.06(d, J=8.7 Hz, 1H), 7.77 (d, J=8.8 Hz, 1H), 7.48(m, 3H), 7.32(d, J=6.9 Hz, 2H), 4.35(br s, 2H), 3.80(br s, 4H), 3.59(s, 2H), 3.25(br s, 2H). Mass: 402.04(M++1-HCl).

Provenance & Evidence