Hydrochloric Acid → HCID 60209020, compound

Participants

Reaction Steps

To a solution of Example 4 (0.065 g, 0.202 mmoles) in THF (2 ml), was added hydrochloric acid in diethyl ether(2 ml) at 0° C. and stirred for 30 min. The precipitate formed was filtered, washed with pentane and dried to afford the title compound as off-white solid (0.043 g, 60% yield. MP: 208-209° C. 1H-NMR (δ ppm, DMSO-D6, 400 MHz): δ 11.42(br s, 1H), 8.08(d, J=7.8 Hz, 1H), 7.90 (t, J=8.1 Hz, 1H), 7.79(d, J=8.4 Hz, 1H), 7.55(t, J=7.5 Hz,1H), 7.49-7.44(m,3H), 7.33(d, J=7.3 Hz,2H), 4.24(br s, 2H), 3.81(br s, 5H), 3.08(br s, 3H). 322.10(M++1-HCl).

Provenance & Evidence