Hydrochloric Acid → Phenol, 5-chloro-2-nitro-

Participants

Reaction Conditions

Reaction Steps

57.6 g (0.3 mol) of 2,4-dichloronitrobenzene were admixed with 10 g (0.014 mol) of dimethyldi(ethoxypolyoxypropyl)ammonium chloride and 150 ml of 20% by weight strength NaOH at 60° C. The two-phase reaction mixture was stirred for 21 hours at 100° C. and subsequently brought to pH 1 using HCl. Amount of 5-chloro-2-nitrophenol formed: after 21 hours: 40 GC area-%.

Provenance & Evidence