Hydrochloric Acid → HCID 60209021, compound

Participants

Reaction Steps

To a solution of Example 18 (0.080 g, 0.235 mmoles) in THF (2 ml), was added hydrochloric acid in diethyl ether (2 ml) at 0° C. and stirred for 30 min. The precipitate formed was filtered, washed with pentane and dried to afford the title compound as yellow solid (0.080 g, 90% yield. MP: 225-229° C. 1H-NMR (δ ppm, DMSO-D6, 400 MHz): δ 8.08(d, J=6.6 Hz, 1H), 7.95 (t, J=7.3 Hz, 1H), 7.78(d, J=8.2 Hz, 1H), 7.55(t, J=7.6 Hz, 1H), 7.38(m,4H), 4.30(br s, 2H), 3.88(br s, 6H), 3.12(br s, 2H).). Mass: 340.09(M+1-HCl).

Provenance & Evidence