HCID 10047638, compound → HCID 10070660, compound

HRID 2396513Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[N:11]=[C:10]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27])[CH:9]=2)=[CH:4][CH:3]=1.N[C:32]1C=CC(C2C=C(C3C=CC=CC=3)N=C(OCCCCC(C)(C)C(OC)=O)C=2)=CC=1.CNC1C=CC(C2C=C(C3C=CC=CC=3)N=C(OCCCCC(C)(C)C(OC)=O)C=2)=CC=1>>[CH3:32][NH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[N:11]=[C:10]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27])[CH:9]=2)=[CH:4][CH:3]=1

Participants

Reactant 3

HCID 10047638HCID 10047638, compound

HCID 10431342HCID 10431342, compound

HCID 18987194HCID 18987194, compound

Product 1

HCID 10070660HCID 10070660, compound

Procedure

When the procedure of Example 16 is followed and ethyl 6-{[4-(4-aminophenyl)-6-phenyl-2-pyridyl]oxy}hexanoate is replaced with methyl 6-{[4 -(4-aminophenyl)-6-phenyl-2-pyridyl]oxy}-2,2-dimethylhexanoate then the compound prepared is methyl 6-{[4-(4-methylaminophenyl)-6-phenyl-2-pyridyl]oxy}-2,2-dimethylhexanoate. (m.p.=77° C.)

Workup

customthe compound prepared

Sources & evidence

ORD record: ord-2595067e21014f1983ad3ed3dc08e812
Source dataset: uspto-grants-1996_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05492915

Reaction notes

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