HCID 18987251, compound → 3,5-diphenylphenol

HRID 2396521Notes

Reaction equation

HRID 2396521 reaction equation
[C:1]1([C:7]2[CH:8]=[C:9]([O:19]C)[CH:10]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH+]1C=CC=CC=1>>[C:1]1([C:7]2[CH:8]=[C:9]([OH:19])[CH:10]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 18987251HCID 18987251, compoundHCID 21584435Pyridinium hydrochloride

Product 1

HCID 35546253,5-diphenylphenolYield 85%

Procedure

A mixture of 4.7 g of 3,5-diphenyl-anisole and 5.3 g of pyridinium hydrochloride was heated for 5 hours to 185° C. After cooling, the residue was partitioned between 100 cc of diethyl ether and 120 cc of water. The organic layer wes then washed with water, dried (Na2SO4) and evaporated. The resultant residue was suspended in 50 cc of n-hexane and filtered to give 3.75 g (85%) of 3,5-diphenyl-phenol as a white solid. (m.p.=97° C.)

Workup

  1. temperaturewas heated for 5 hours to 185° C
  2. temperatureAfter cooling
  3. customthe residue was partitioned between 100 cc of diethyl ether and 120 cc of water
  4. washThe organic layer wes then washed with water
  5. dry with materialdried (Na2SO4)
  6. customevaporated
  7. filtrationfiltered

Sources & evidence

ORD record
ord-f6a5dd0f9eb8461c9f60d568e1eb78ce
Source dataset
uspto-grants-1996_02
Patent number
US05492915

Reaction notes

Loading…