HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 2,2-Dimethyl-6-[(4,6-diphenyl-2-pyridyl)oxy]hexanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Methyl 2,2-dimethyl-6-[(4,6-diphenyl-2-pyridyl)oxy]hexanoate | HCID 11741909 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2,2-Dimethyl-6-[(4,6-diphenyl-2-pyridyl)oxy]hexanoic acid | HCID 10023244 | — |
Reaction Steps
The procedure in Example 6 is followed but using methyl 2,2-dimethyl-6-[(4,6-diphenyl-2-pyridyl) oxy]hexanoate (5 g), potassium hydroxide pellets (1.1 g) and ethanol (100 cc). The reaction mixture is refluxed for 24 hours. The product is purified by chromatography under pressure on silica gel (30-60 mm; eluent: n-hexane-ethyl acetate 8-2), white crystals (m.p.=115° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05492915 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-92b6da61f2624267965e054e17109f9a |
| Source note | uspto-grants-1996_02 |