HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3,4-Methylenedioxyphenyl)-6-phenyl-2-pyridinone → Ethyl 2-methyl-6-{[4-(3,4-methylenedioxyphenyl)-6-phenyl-2-pyridyl]oxy}hexanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3,4-Methylenedioxyphenyl)-6-phenyl-2-pyridinone | HCID 10379516 | — |
| Reactant | Ethyl 6-bromo-2-methylhexanoate | HCID 14946850 | — |
| Catalyst | HCID 178418647 | HCID 178418647 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Ethyl 2-methyl-6-{[4-(3,4-methylenedioxyphenyl)-6-phenyl-2-pyridyl]oxy}hexanoate | HCID 10049280 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
The procedure in Example 5 is followed but using 4-(3,4-methylenedioxyphenyl)-6-phenyl-2-pyridinone (2.5 g), ethyl 6-bromo-2-methylhexanoate (4 g), silver carbonate (1.2 g) and dimethylformamide (100 cc). The reaction mixture is heated at 100° C. for 72 hours. The product is purified by chromatography under pressure on silica gel (30-60 mm; eluent: n-hexane-ethyl acetate 9-1). (yellowish oil)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05492915 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-a5548e69b31f48139d45d1a927f4790b |
| Source note | uspto-grants-1996_02 |