Ethylorthoformate → Ethyl 2-(2-ethyl-3,4,5,6-tetrafluorobenzoyl)-3-ethoxyacrylate

HRID 2396969Notes

Reaction equation

[CH2:1]([C:3]1[C:16]([F:17])=[C:15]([F:18])[C:14]([F:19])=[C:13]([F:20])[C:4]=1[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])=[O:6])[CH3:2].[CH:21]([O-])([O-])[O:22][CH2:23][CH3:24]>>[CH2:1]([C:3]1[C:16]([F:17])=[C:15]([F:18])[C:14]([F:19])=[C:13]([F:20])[C:4]=1[C:5]([C:7](=[CH:21][O:22][CH2:23][CH3:24])[C:8]([O:10][CH2:11][CH3:12])=[O:9])=[O:6])[CH3:2]

Participants

Reactant 2

HCID 53630039Ethylorthoformate

HCID 53931173Ethyl 2-ethyl-3,4,5,6-tetrafluorobenzoylacetate

Product 1

HCID 54246622Ethyl 2-(2-ethyl-3,4,5,6-tetrafluorobenzoyl)-3-ethoxyacrylate

Procedure

Employing ethyl 2-ethyl-3,4,5,6-tetrafluorobenzoylacetate (8 g) and ethyl orthoformate (6.1 g), the procedure of Reference Example 20 is repeated to give ethyl 2-(2-ethyl-3,4,5,6-tetrafluorobenzoyl)-3-ethoxyacrylate.

Sources & evidence

ORD record: ord-3d35518acae447fd84b5e970889eb5e4
Source dataset: uspto-grants-1996_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05495020

Reaction notes

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