HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 14651268, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 14651269 | HCID 14651269 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 14651268 | HCID 14651268 | 93.3% |
Reaction Steps
Employing ethyl 1-ethyl-5-methyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-caboxylate (6.51 g) and conc. hydrochloric acid : 90% acetic acid (1:4) (100 ml), the procedure of Reference Example 23 is repeated to give 1-ethyl-5-methyl-6,7,8-trifluoro-1,4-dihydro-4 -oxoquinoline-3-carboxylic acid (5.53 g), as colorless needles (recrystallized from dichloromethane--n-hexane), m.p. 203°-204° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05495020 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-1b99d463b7af4e7fa0c06192dff998d6 |
| Source note | uspto-grants-1996_02 |