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HRID2397003

反应详情

EQUATION

反应方程式

HRID 2397003 的结构方程式

REACTANTS

反应物

3
结构：COc1ncnc2nc[nH]c12
HCID70632

6-Methoxypurine

C6H6N4O

结构：C[C@H](O)[C@@]1(c2ccc(F)cc2F)CO1
HCID10631861

未命名化合物

结构：COc1ncnc2ncn([C@H](C)[C@@]3(c4ccc(F)cc4F)CO3)c12
HCID22859142

未命名化合物

PRODUCTS

生成物

1
结构：COc1ncnc2c1ncn2[C@H](C)[C@@]1(c2ccc(F)cc2F)CO1
HCID18657628

未命名化合物

收率 21.1%

PROCEDURE

实验过程

Using (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol (523 mg) and 6-methoxypurine 1/2 hydrate (415 mg), (2S)-2-(2,4-difluorophenyl)-2-[(1R)-1-[6-methoxy-7(7H)purinyl]ethyl]oxirane (205 mg) and (2S)-2-(2,4-difluorophenyl)-2-[(1R)-1-[6-methoxy-9(9H)-purinyl]ethyl]oxirane (183 mg) were obtained as a white powder respectively by the same way as in Reference Example 2.