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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397005Generated: October 29, 2026

6-Chloropurine → HCID 57145125, compound

https://huagongshe.com/reaction/2397005

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-ChloropurineHCID 5359277—
Reactant(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanolHCID 10631861—
ProductHCID 57145125HCID 5714512547.9%

Reaction Steps

Using (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol (607 mg) and 6-chloropurine (422 mg), (2S)-2-[(1R)-1-[6-chloro-9(9H)-purinyl]ethyl]-2-(2,4-difluorophenyl)oxirane (440 mg) was obtained as a white powder by the same way as in Reference Example 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05495024
Source datasetuspto-grants-1996_02
ORD IDord-15a794e6c0884084a1fa137e32ff2d5f
Source noteuspto-grants-1996_02