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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397098Generated: October 29, 2026

(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene

https://huagongshe.com/reaction/2397098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-methanolHCID 19186—
ReactantBenzenesulfonyl fluoride, p-chloro-HCID 94992—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventTetrahydrofuranHCID 8028—
Product1-(Fluoromethyl)-4-phenylbenzeneHCID 8603785411%

Provenance & Evidence

DOI10.1021/jacs.8b01523
Source datasetDeoxyfluorination screen
ORD IDord-b9663791e2954271b97b6c89f6f776a1
Source noteDeoxyfluorination screen