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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397102Generated: October 30, 2026

(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene

https://huagongshe.com/reaction/2397102

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-methanolHCID 19186—
ReactantPyridine-2-sulfonyl FluorideHCID 11615218—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventTetrahydrofuranHCID 8028—
Product1-(Fluoromethyl)-4-phenylbenzeneHCID 8603785412%

Provenance & Evidence

DOI10.1021/jacs.8b01523
Source datasetDeoxyfluorination screen
ORD IDord-07adcd82ad3c48a989f866aba6a11291
Source noteDeoxyfluorination screen