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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397106Generated: November 1, 2026

(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene

https://huagongshe.com/reaction/2397106

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-methanolHCID 19186—
Reactant4-(Trifluoromethyl)benzenesulfonyl fluorideHCID 85828235—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventTetrahydrofuranHCID 8028—
Product1-(Fluoromethyl)-4-phenylbenzeneHCID 8603785417%

Provenance & Evidence

DOI10.1021/jacs.8b01523
Source datasetDeoxyfluorination screen
ORD IDord-157e8c0fa0214aaa90d0236d76e1298f
Source noteDeoxyfluorination screen