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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397109Generated: November 2, 2026

(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene

https://huagongshe.com/reaction/2397109

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-methanolHCID 19186—
Reactant4-(Trifluoromethyl)benzenesulfonyl fluorideHCID 85828235—
Reagenttert-Butylimino-tri(pyrrolidino)phosphoraneHCID 3856267—
SolventTetrahydrofuranHCID 8028—
Product1-(Fluoromethyl)-4-phenylbenzeneHCID 8603785499%

Provenance & Evidence

DOI10.1021/jacs.8b01523
Source datasetDeoxyfluorination screen
ORD IDord-7003937ca6bf4d3f96e23b65b380d548
Source noteDeoxyfluorination screen