HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397112Generated: October 29, 2026
(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene
https://huagongshe.com/reaction/2397112
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (1,1'-Biphenyl)-4-methanol | HCID 19186 | — |
| Reactant | 4-Nitrobenzenesulfonyl fluoride | HCID 188246 | — |
| Reagent | 2-tert-Butyl-1,1,3,3-tetramethylguanidine | HCID 3571581 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-(Fluoromethyl)-4-phenylbenzene | HCID 86037854 | 83% |
Provenance & Evidence
| DOI | 10.1021/jacs.8b01523 |
|---|
| Source dataset | Deoxyfluorination screen |
|---|
| ORD ID | ord-d134dca894944bde9ed98b3336f99b95 |
|---|
| Source note | Deoxyfluorination screen |
|---|
