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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397113Generated: October 28, 2026

(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene

https://huagongshe.com/reaction/2397113

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-methanolHCID 19186—
Reactant4-Nitrobenzenesulfonyl fluorideHCID 188246—
Reagenttert-Butylimino-tri(pyrrolidino)phosphoraneHCID 3856267—
SolventTetrahydrofuranHCID 8028—
Product1-(Fluoromethyl)-4-phenylbenzeneHCID 8603785491%

Provenance & Evidence

DOI10.1021/jacs.8b01523
Source datasetDeoxyfluorination screen
ORD IDord-1080d2ef9d2d4a2889515ad067f16e3f
Source noteDeoxyfluorination screen