Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397115Generated: October 30, 2026

(1,1'-Biphenyl)-4-methanol → 1-(Fluoromethyl)-4-phenylbenzene

https://huagongshe.com/reaction/2397115

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-methanolHCID 19186—
ReactantPerfluoro-1-butanesulfonyl fluorideHCID 67814—
Reagent7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-eneHCID 123583—
SolventTetrahydrofuranHCID 8028—
Product1-(Fluoromethyl)-4-phenylbenzeneHCID 8603785437%

Provenance & Evidence

DOI10.1021/jacs.8b01523
Source datasetDeoxyfluorination screen
ORD IDord-300c82cd300f4a7dad5d1efa50c65503
Source noteDeoxyfluorination screen