Methyl iodide → HCID 20358708, compound

HRID 2397244Notes

Reaction equation

HRID 2397244 reaction equation
[C:1]1([C:7]2[O:8][C:9]3[CH:15]=[CH:14][C:13]([CH:16]([CH3:19])[C:17]#[N:18])=[CH:12][C:10]=3[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:20]I>>[C:1]1([C:7]2[O:8][C:9]3[CH:15]=[CH:14][C:13]([C:16]([CH3:20])([CH3:19])[C:17]#[N:18])=[CH:12][C:10]=3[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 30397732-(2-Phenyl-1,3-benzoxazol-5-yl)propanenitrile

Product 1

HCID 20358708HCID 20358708, compound

Procedure

By treatment of 2-(2-phenyl-5-benzoxazolyl)propionitrile with methyl iodide in the manner described in Example 12, there was obtained 2-(2-phenyl-5-benzoxazolyl)isobutyronitrile which, on treatment with concentrated hydrochloric acid as described in Example 1(f), yielded 2-(2-phenyl-5-benzoxazolylisobutyric acid, m.p. 92° -95° C.

Sources & evidence

ORD record
ord-d2d7613aa2c2492491888f39f4a57060
Source dataset
uspto-grants-1977_05
Patent number
US04021440

Reaction notes

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