1-Octanol → Octyl 2-aminobenzoate

Participants

Reaction Steps

To a methanolic solution of sodium methoxide (prepared from 30 ml of methanol and 0.2 g. of sodium) were added 91 g. of methyl anthranilate and 78 g. of 1-octanol. The reaction mixture was heated at 90° C. for 0.75 hour and at 125° C. for 0.75 hour while methanol was removed by distillation. The residue was washed with water, dried, and distilled. n-Octyl anthranilate was obtained as a clear liquid, b.p. 139°-144° C. at about 0.5 mm.

Provenance & Evidence