4-tert-Butylphenol → HCID 14715851, compound

HRID 2397270Notes

Reaction equation

HRID 2397270 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[C:12]12[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=1)[NH:17]C(=O)O[C:13]2=[O:14]>>[C:13]([O:11][C:8]1[CH:7]=[CH:6][C:5]([C:1]([CH3:4])([CH3:2])[CH3:3])=[CH:10][CH:9]=1)(=[O:14])[C:12]1[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=1)[NH2:17]

Participants

3

Reactant 2

HCID 73934-tert-ButylphenolHCID 8359Isatoic Anhydride

Product 1

HCID 14715851HCID 14715851, compound

Procedure

To 112.5 g. of p-tert-butylphenol heated at 100°-120° C. there was added in portions 123 g. of isatoic anhydride during about 0.75 hour. The reaction mixture was allowed to cool and was then extracted with hot ethyl alcohol from which the crude ester crystallized upon cooling. Recrystallization from n-heptane afforded the crystalline ester mp 142°-143° C.

Workup

  1. additionthere was added in portions 123 g
  2. temperatureto cool
  3. extractionwas then extracted with hot ethyl alcohol from which the crude ester
  4. customcrystallized
  5. temperatureupon cooling
  6. customRecrystallization from n-heptane

Sources & evidence

ORD record
ord-c4b75c24d2bd47668ee6f92e7637a9dc
Source dataset
uspto-grants-1977_05
Patent number
US04021470

Reaction notes

Loading…