HRID2397287

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6386

tert-Butyl alcohol

C4H10O

HCID24386

Thionyl chloride

Cl2OS

$反应SMILES：CC(=CC(=O)O)/C=C\CC(C)CCCC(C)C$

HCID86734009

未命名化合物

PRODUCTS

产物

$反应SMILES：CC(=CC(=O)OC(C)(C)C)/C=C\CC(C)CCCC(C)C$

HCID86734713

未命名化合物

PROCEDURE

实验过程

One gram of thionyl chloride is added with stirring at room temperature to 0.5 g. of trans/cis 3,7,11-trimethyldodeca-2,4-dienoic acid and the mixture heated at about 50° for 10 minutes. Excess thionyl chloride is removed by evaporation and then t-butyl alcohol (about 2 equivalents) is added and the mixture heated at about 50° for about 5 minutes. Excess t-butyl alcohol is removed by evaporation to yield trans/cis t-butyl 3,7,11-trimethyldodeca-2,4-dienoate which is purified by chromatography.

WORKUP

后处理

customExcess thionyl chloride is removed by evaporation
temperaturethe mixture heated at about 50° for about 5 minutes
customExcess t-butyl alcohol is removed by evaporation