4-Chlorophenol → Benzene, 1,1'-[oxybis(methyleneoxy)]bis[4-chloro-

Participants

Reaction Steps

A solution of 16.2 g (0.1 mole) of bis(acetoxymethyl) ether and 39 g (0.30 mole) of p-chlorophenol in 80 ml of o-dichlorobenzene were treated with 1.0 g of neutral aluminum oxide (80-240 mesh) and heated to reflux (pot temp. 180°-185° C.). Distillate was removed at about 10 ml/hr over a 4 hour period. The reaction mixture was filtered hot, stripped in vacuo, and triturated with light petroleum ether to furnish 19.0 g (61% yield) of product, mp 53.5°-4° C.

Provenance & Evidence