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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397321Generated: October 28, 2026

Potassium Iodide → HCID 21437252, compound

https://huagongshe.com/reaction/2397321

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium IodideHCID 4875—
ReactantTetrahydrofuranHCID 8028—
ReactantN-MethylcyclopropanamineHCID 11029756—
ReactantHCID 20291813HCID 20291813—
ProductHCID 21437252HCID 21437252—

Reaction Steps

In the manner given in Example 2, potassium iodide and 8-chloro-1-(chloromethyl)-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in tetrahydrofuran is treated with methylcyclopropylamine to give 8-chloro-1-[(cyclopropylmethylamino)methyl]-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04021441
Source datasetuspto-grants-1977_05
ORD IDord-2f04f889220f4dd284622906826b2ce4
Source noteuspto-grants-1977_05