HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 21437252, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | (Cyclopropylmethyl)ammonium chloride | HCID 81671 | — |
| Reactant | HCID 20291813 | HCID 20291813 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21437252 | HCID 21437252 | — |
Reaction Steps
In the manner given in Example 3, a solution of potassium hydroxide and (cyclopropylmethyl)amine hydrochloride is treated with a solution of 8-chloro-1-(chloromethyl)-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]-benzodiazepine and potassium iodide in tetrahydrofuran to give 8-chloro-1-[[(cyclopropylmethyl)amino]methyl]-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04021441 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-1bbd48c2a2204230af171ed2478a3e02 |
| Source note | uspto-grants-1977_05 |