HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-(3-Aminophenyl)ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | m-Nitroacetophenone | HCID 8494 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 1-(3-Aminophenyl)ethanol | HCID 222461 | 75% |
Reaction Steps
m-Nitroacetophenone (66.0 g., 0.40 mole), water containing 0.70 mole phosphoric acid (300 ml.), and 5% palladium on carbon (2.0 g.) were hydrogenated as in Example II until hydrogen absorption ceased (2 hours). Work-up after neutralization with 1.40 moles potassium hydroxide gave m-amino-α-methylbenzyl alcohol in 75% yield which was 99% pure by GLC and contained 0.8% m-ethylaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04021487 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-34803fe49ce143cc9add29047dd2a79a |
| Source note | uspto-grants-1977_05 |