Cyclohexylamine → HCID 53953756, compound

HRID 2397388Notes

Reaction equation

HRID 2397388 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([C:15](=O)[CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:11][CH:10]=1.C1(N)CCCCC1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 7965CyclohexylamineHCID 21437985HCID 21437985, compound

Product 1

HCID 53953756HCID 53953756, compoundYield 97%

Procedure

Prepared analogous to Example 12 from 4-(2' ,3'-dichloro-4-biphenylyl)-4-oxo-butyric acid. Yield: 97% of theory, m.p. 70°-71° C. (from petroleum ether/cyclohexane); melting point of the cyclohexylamine salt: 163°-165° C.

Workup

  1. custom163°-165° C.

Sources & evidence

ORD record
ord-9dde3bbb97c848a0836a9b2ff19432b8
Source dataset
uspto-grants-1977_05
Patent number
US04021479

Reaction notes

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