Cyclohexylamine → HCID 21437927, compound

HRID 2397391Notes

Reaction equation

HRID 2397391 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([C:14](=[O:20])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:10][CH:9]=1.C1(N)CCCCC1>>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([OH:20])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 7965CyclohexylamineHCID 14116664HCID 14116664, compound

Product 1

HCID 21437927HCID 21437927, compoundYield 53.4%

Procedure

Prepared analogous to Example 25 from 4-(2'-bromo-4-biphenylyl)-4-oxo-butyric acid. Melting point of the cyclohexylamine salt: 162°-163° C.; yield: 53.4% of theory.

Workup

  1. custom162°-163° C.

Sources & evidence

ORD record
ord-4fce8616b6bc41db8039d336a36a3e7f
Source dataset
uspto-grants-1977_05
Patent number
US04021479

Reaction notes

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