Cyclohexylamine → HCID 21437934, compound

HRID 2397418Notes

Reaction equation

HRID 2397418 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([C:15](=[O:21])[CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:11][CH:10]=1.C1(N)CCCCC1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([CH:15]([OH:21])[CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 7965CyclohexylamineHCID 21437985HCID 21437985, compound

Product 1

HCID 21437934HCID 21437934, compoundYield 75%

Procedure

Prepared analogous to Example 25 from 4-(2',3'-dichloro-4-biphenylyl)-4-oxo-butyric acid. Yield: 75% of theory, m.p. 134°-135° C. (decomp.). Melting point of the cyclohexylamine salt: 158° C. (decomp.).

Sources & evidence

ORD record
ord-fe3cbdb4ce914ee390b3dc26b7fe1de1
Source dataset
uspto-grants-1977_05
Patent number
US04021479

Reaction notes

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