Cyclohexylamine → HCID 21437930, compound

HRID 2397420Notes

Reaction equation

HRID 2397420 reaction equation
[NH:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][C:14]([C:17](=[O:23])[CH2:18][CH2:19][C:20]([OH:22])=[O:21])=[CH:13][CH:12]=2)=[CH:7][C:6]=1[Br:24])[C:2]([CH3:4])=[O:3].C1(N)CCCCC1>C(O)C>[C:2]([NH:1][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][C:14]([CH:17]([OH:23])[CH2:18][CH2:19][C:20]([OH:22])=[O:21])=[CH:13][CH:12]=2)=[CH:7][C:6]=1[Br:24])(=[O:3])[CH3:4]

Participants

4

Reactant 2

HCID 7965CyclohexylamineHCID 21437911HCID 21437911, compound

Product 1

HCID 21437930HCID 21437930, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogous to Example 25 from 4-(4'-acetamino-3'-bromo-4-biphenylyl)-4-oxo-butyric acid. Yield: 53% of theory, m.p. 125°-126° C. Melting point of the cyclohexylamine salt: 165°-167° C. (from ethanol).

Sources & evidence

ORD record
ord-deb0dea37cab42f3819c4a24a284a25d
Source dataset
uspto-grants-1977_05
Patent number
US04021479

Reaction notes

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