HCID 9900147, compound → HCID 21437922, compound

HRID 2397421Notes

Reaction equation

HRID 2397421 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([C:8](=[O:14])[CH2:9][CH2:10][C:11]([OH:13])=[O:12])[CH:5]=[CH:4][C:3]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C1C=CC=CC=1>[F:1][C:2]1[CH:7]=[C:6]([CH:8]([OH:14])[CH2:9][CH2:10][C:11]([OH:13])=[O:12])[CH:5]=[CH:4][C:3]=1[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 1

HCID 9900147HCID 9900147, compound

Product 1

HCID 21437922HCID 21437922, compoundYield 74%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Prepared analogous to Example 25 from 4-(2-fluoro-4-biphenylyl)-4-oxo-butyric acid. Yield: 74% of theory, m.p. 133°-135° C. (from benzene).

Sources & evidence

ORD record
ord-fb7ad37ffe614916b1fdeba5c31e47c9
Source dataset
uspto-grants-1977_05
Patent number
US04021479

Reaction notes

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