HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 21313361, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Pyridine-2-carbonyl chloride | HCID 135034 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 3-[2-(2-Cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole | HCID 21313365 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21313361 | HCID 21313361 | — |
Reaction Steps
Reaction of the 3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole described in Example 1 above with sodium hydride in DMF, and reaction of the resulting sodium salt with 2-pyridine carbonyl chloride using the procedure described above in Example 1 affords 1-(2-pyridylcarbonyl)-3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04021431 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-6cac6af26fee414aa02af098abb348de |
| Source note | uspto-grants-1977_05 |