Formaldehyde → HCID 21313415, compound

HRID 2397503Notes

Reaction equation

HRID 2397503 reaction equation
[C:1]([N:9]1[C:17]2[C:12](=[CH:13][C:14]([NH2:18])=[CH:15][CH:16]=2)[C:11]([CH2:19][CH2:20][N:21]2[CH2:26][CH2:25][CH2:24][CH:23]([CH2:27][CH:28]3[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]3)[CH2:22]2)=[C:10]1[CH3:34])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:35]=O>C(O)=O>[C:1]([N:9]1[C:17]2[C:12](=[CH:13][C:14]([NH:18][CH3:35])=[CH:15][CH:16]=2)[C:11]([CH2:19][CH2:20][N:21]2[CH2:26][CH2:25][CH2:24][CH:23]([CH2:27][CH:28]3[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]3)[CH2:22]2)=[C:10]1[CH3:34])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 21313362HCID 21313362, compound

Product 1

HCID 21313415HCID 21313415, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

Reaction of the 1-benzoyl-3-[2-(3-cyclohexylmethylpiperidino)ethyl]-5-amino-2-methylindole described above in Example 95 with formaldehyde and formic acid affords 1-benzoyl-3-[2-(3-cyclohexylmethylpiperidino)ethyl]-5-methylamino-2-methylindole.

Sources & evidence

ORD record
ord-d45cf10cc93c44cbb80bb424d21c1e34
Source dataset
uspto-grants-1977_05
Patent number
US04021431

Reaction notes

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