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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2397538Generated: October 30, 2026

1H-Indole, 1-ethyl-2-methyl- → Benzoic acid, 2-[4-(diethylamino)benzoyl]-

https://huagongshe.com/reaction/2397538

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indole, 1-ethyl-2-methyl-HCID 170432—
Reactant4-(Dimethylamino)phthalic anhydrideHCID 11435442—
ProductBenzoic acid, 2-[4-(diethylamino)benzoyl]-HCID 11055585—

Reaction Steps

Homophthalic anhydride (I) can be reacted mol-for-mol with a compound such as 1-ethyl-2-methylindole (T) in the presence of a catalyst, as previously disclosed, to yield keto-acid (II).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04022771
Source datasetuspto-grants-1977_05
ORD IDord-3446d5bbfcdf4286ae71a187f047c004
Source noteuspto-grants-1977_05