HCID 21436038, compound → HCID 9920560, compound

HRID 2397545Notes

Reaction equation

HRID 2397545 reaction equation
[C:1]([NH:4][C:5]1[C:14]([NH2:15])=[N:13][C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]=1)(=O)[CH3:2]>C(O)(=O)C>[CH3:2][C:1]1[NH:15][C:14]2=[N:13][C:12]3[C:7]([N:6]=[C:5]2[N:4]=1)=[CH:8][CH:9]=[CH:10][CH:11]=3

Participants

3

Reactant 1

HCID 21436038HCID 21436038, compound

Product 1

HCID 9920560HCID 9920560, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 19 parts of 2-acetamido-3-aminoquinoxaline in 200 parts of glacial acetic acid was heated at reflux for 30 minutes. Concentration in vacuo left a pale yellow solid. Recrystallization from ethyl acetate-methanol (2:1) gave 16.8 parts of pale yellow 2-methyl-1H-imidazo[4,5-b]quinoxaline, mp 360° (dec.).

Workup

  1. temperatureat reflux for 30 minutes
  2. concentrationConcentration in vacuo
  3. waitleft a pale yellow solid
  4. customRecrystallization from ethyl acetate-methanol (2:1)

Sources & evidence

ORD record
ord-285f94bc47094ddfa000c5ee780ed0ae
Source dataset
uspto-grants-1977_05
Patent number
US04022777

Reaction notes

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