HCID 21436337, compound → HCID 21436327, compound

HRID 2397616Notes

Reaction equation

HRID 2397616 reaction equation
[OH:1][CH:2]([CH2:21][CH2:22][CH2:23][CH2:24]C)[CH2:3][CH2:4][N:5]1[C:9](=[O:10])[CH2:8][S:7][CH:6]1[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([O:19]C)=[O:18].O1CCCCC1CCN1C(=O)CSC1CCCCCCC(OC)=O>>[O:1]1[CH2:24][CH2:23][CH2:22][CH2:21][CH:2]1[CH2:3][CH2:4][N:5]1[C:9](=[O:10])[CH2:8][S:7][CH:6]1[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18]

Participants

3

Reactant 2

HCID 21436337HCID 21436337, compoundHCID 21436358HCID 21436358, compound

Product 1

HCID 21436327HCID 21436327, compound

Procedure

This compound is prepared essentially by the same method as described in Example 1, Step C, except that the methyl 7-[3-(3-hydroxyoctyl)-4-oxo-2-thiazolidinyl]heptanoate is replaced by methyl 7-{3-[2-(tetrahydro-2H-pyran-2-yl)-ethyl]-4-oxo-2-thiazolidinyl}heptanoate. After careful chromatographic purification on silica gel, the title compound is obtained as a viscous, pale yellow oil.

Workup

  1. customThis compound is prepared essentially by the same method
  2. customAfter careful chromatographic purification on silica gel

Sources & evidence

ORD record
ord-6b11029971a9490c85038d256141b0b8
Source dataset
uspto-grants-1977_05
Patent number
US04022794

Reaction notes

Loading…