2-[1-(Tetrahydro-2H-pyran-2-yloxy)cyclohexyl]acetonitrile → 1-Amino-2-[1-(tetrahydro-2H-pyran-2-yloxy)cyclohexyl]ethane

HRID 2397618Notes

Reaction equation

HRID 2397618 reaction equation
[O:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[O:7][CH:8]([CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH2:9][C:10]#[N:11].O1CCCCC1OC1(CC#N)CCCCC1>>[NH2:11][CH2:10][CH2:9][C:8]1([O:7][CH:2]2[CH2:3][CH2:4][CH2:5][CH2:6][O:1]2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 128971812-[1-(Tetrahydro-2H-pyran-2-yloxy)cyclohexyl]acetonitrileHCID 234680723-(Tetrahydro-2H-pyran-2-yloxy)caprylonitrile

Product 1

HCID 128971821-Amino-2-[1-(tetrahydro-2H-pyran-2-yloxy)cyclohexyl]ethane

Procedure

This compound is prepared essentially by the same method as described in Example 1, Step A-3, except that the 3-(tetrahydro-2H-pyran-2-yloxy)caprylonitrile is replaced by a 2-[1-(tetrahydro-2H-pyran-2-yloxy)cyclohexyl]acetonitrile. This process yields the title compound as a pale yellow oil.

Workup

  1. customThis compound is prepared essentially by the same method

Sources & evidence

ORD record
ord-90f026f8da9c450b8ef6976d38a910c4
Source dataset
uspto-grants-1977_05
Patent number
US04022794

Reaction notes

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