Sulfuric Acid → HCID 1627481, compound

HRID 2397785Notes

Reaction equation

HRID 2397785 reaction equation
[Cl:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([Cl:10])[C:5]([Cl:11])=[C:4]([Cl:12])[C:3]=1[Cl:13].S(=O)(=O)(O)[OH:15]>>[Cl:1][C:2]1[C:7]([C:8]([NH2:9])=[O:15])=[C:6]([Cl:10])[C:5]([Cl:11])=[C:4]([Cl:12])[C:3]=1[Cl:13]

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 30363Pentachlorobenzonitrile2×

Product 1

HCID 1627481HCID 1627481, compoundYield 94%

Procedure

A mixture of 18.0 gms. pentachlorobenzonitrile and 200 ml concentrated sulfuric acid (97 weight % H2SO4) was heated to 145° C. over a period of approximately 40 min. Complete dissolution of the pentachlorobenzonitrile was observed to occur at 130° C. thereby giving a pale straw solution. When cool, the reaction mixture was poured onto ice and the white solid thereby formed was isolated by filtration. In this manner there was formed 18.0 gms. (94% yield) pentachlorobenzamide. Identity of the product was established with the aid of both analytical and spectral data.

Workup

  1. additionA mixture of 18.0 gms
  2. customto occur at 130° C.
  3. customthereby giving a pale straw solution
  4. temperatureWhen cool
  5. additionthe reaction mixture was poured onto ice
  6. customthe white solid thereby formed
  7. customwas isolated by filtration
  8. customIn this manner there was formed 18.0 gms

Sources & evidence

ORD record
ord-52411cd1ca0e4792aa25bedc9a4c7359
Source dataset
uspto-grants-1977_05
Patent number
US04022830

Reaction notes

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