Chlorine → 2-Amino-4-bromo-5-chloropyridin-3-ol

HRID 2397844Notes

Reaction equation

HRID 2397844 reaction equation

[NH2:1][C:2]1[C:7]([OH:8])=[C:6]([Br:9])[CH:5]=[CH:4][N:3]=1.[Cl:10]Cl>>[NH2:1][C:2]1[C:7]([OH:8])=[C:6]([Br:9])[C:5]([Cl:10])=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 24526Chlorine

HCID 214366802-Amino-4-bromopyridin-3-ol

Product 1

HCID 214366672-Amino-4-bromo-5-chloropyridin-3-ol

Procedure

The procedure of Example I-12 is followed with 2-amino-4 -bromo-3-pyridinol and chlorine to give 2-amino- 4-bromo-5-chloro-3-pyridinol.

Sources & evidence

ORD record: ord-09d27e1aa0bf4ef1b452256cd1ada3fd
Source dataset: uspto-grants-1977_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04022897

Reaction notes

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