HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxybenzyl alcohol → 4-Methyloxybenzyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxybenzyl alcohol | HCID 7738 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Methyloxybenzyl chloride | HCID 69993 | — |
Reaction Steps
To 138.0 g of p-methoxybenzyl alcohol in 500 ml of dry chloroform is added, dropwise, 119 g of thionyl chloride. Subsequently, the mixture is stirred and heated under reflux for 2 hours, concentrated from the steam bath and the residue fractionated to give p-methoxybenzyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04022897 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-1de349cc9ae244f6a3a281a56f185a5c |
| Source note | uspto-grants-1977_05 |